The HOX genes or hometic genes by full name are genes that regulate the development of anatomical structures in various organisms. Once these genes are mutated, part of the body will change shape. Its working mechanism regulates mainly the relevant cell division.

The characteristics of HOX genes are related to the arrangement order, function order, and function position. For example, genes close to the 3’ -end (one end of DNA) work on the front part of the body, including the head. Genes close to 5’ -end work on the back part of the body. The animal world, humans included, has a similar arrangement method, production, and function method of HOX genes.

The HOX genes of all types of organisms have similar expressions, including the dragonfly. This is a basic law.

The regulation works as these. When the downstream regulation genes of the HOX genes change, the individual mutation will occur. By using the gene-editing method, ubx, or the downstream genes of the dragonfly and Li Shan is modified with H3K4 methylation or regulated by non-coding RNA genes, which leads to anatomical structure growth and change following the mutation of the regulatory hierarchy of ubx downstream genes. Once the ubx changes, its interaction with other genes will be affected.

Besides, if the expression of one area in the HOX genes changes, this area will grow and change. For example, when the protein expressed in the ubx and Abd-A does not work, the D11 will induce the forelimb to grow. Another example is when the interaction method of ubx and Abd-A in different areas changes, an appendage will form.

The HOXA gene cluster of the Chromosome 7 that affects the head and upper limb of Li Shan is knocked out. The 3’ -end HOX gene cluster close to the Chromosome 3 is knocked in. Then it is possible to form a chimera of dragonflies and Li Shan.